Trials / Completed
CompletedNCT02780973
Influence of Gender Specific Differences of Saliva Composition on the Development of Dental Erosion - an In-situ Study
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 50 (actual)
- Sponsor
- University of Göttingen · Academic / Other
- Sex
- All
- Age
- 20 Years – 40 Years
- Healthy volunteers
- Accepted
Summary
Healthy volunteers are observationally wearing an intraoral device with bovine tooth samples once for two hours. Afterwards, Calcium release from the bovine enamel and dentin samples is measured after extraoral erosion. Total protein concentration within the formed salivary pellicles on the bovine samples is determined. Further Salivary parameters (unstimulated and stimulated saliva flow rate, pH, buffer capacity, albumin and total protein content as well as concentration of inorganic calcium, phosphate and fluoride) are being measured. The aim of this study is to investigate whether gender differences in the salivary composition correlate with predisposition to erosion.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Wearing of an intraoral device with bovine tooth samples | Wearing of an intraoral device with bovine tooth samples |
Timeline
- Start date
- 2017-02-07
- Primary completion
- 2018-01-18
- Completion
- 2018-01-18
- First posted
- 2016-05-24
- Last updated
- 2024-02-14
Locations
1 site across 1 country: Germany
Source: ClinicalTrials.gov record NCT02780973. Inclusion in this directory is not an endorsement.