Clinical Trials Directory

Trials / Completed

CompletedNCT02776657

Intracoronary Thrombus Detection by Magnetic Resonance Imaging

Non-Invasive Assessment of Intracoronary Thrombosis in Patients With Acute Coronary Syndrome and Chronic Stable Angina Using Magnetic Resonance Imaging.

Status
Completed
Phase
N/A
Study type
Interventional
Enrollment
40 (estimated)
Sponsor
University of Edinburgh · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This study involves the use of Magnetic Resonance Imaging (MRI) to determine whether blood clots can be identified within the blood vessels supplying blood to the heart in patients with angina and who have recently suffered a heart attack.

Detailed description

The majority of heart attacks are caused as a result of small blood clots forming within the blood vessels supplying blood to the heart, obstructing blood flow to the heart muscle. Research has also shown that blood clots may form in the blood vessels of the heart without causing a heart attack. At present, blood clots may be identified by techniques used during invasive coronary angiography, but we wish to determine whether a non-invasive test (MRI scanning) can be used to detect small blood clots within the blood vessels supplying blood to the heart muscle.

Conditions

Interventions

TypeNameDescription
OTHERMagnetic Resonance ImagingEach participant will undergo at least one MRI scan. A small number will be asked to undergo repeat MRI scanning at one and three months following the initial scan.
DEVICEOptical Coherence TomographyParticipants may undergo Optical Coherence Tomography (OCT) during the angiogram procedure in order to detect thrombus within the coronary arteries.
PROCEDUREInvasive Coronary AngiographyThis will be performed as part of usual care and does not constitute part of the research project.

Timeline

Start date
2016-01-14
Primary completion
2017-03-31
Completion
2017-03-31
First posted
2016-05-18
Last updated
2024-06-21

Source: ClinicalTrials.gov record NCT02776657. Inclusion in this directory is not an endorsement.