NCT02775838

Measurements of Kidney Perfusion After Transplantation by Intraoperative Fluorescence Angiography

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 128 (actual)
• Sponsor: University Hospital Erlangen · Academic / Other
• Sex: All
• Age: 18 Years – 99 Years
• Healthy volunteers: Not accepted

Summary

Aim of this clinical study is to establish a novel technique, the so called intraoperative fluorescence angiography, for kidney graft perfusion visualization during the transplant procedure.

Detailed description

Additional to the common transplant procedure, measurements of the graft perfusion should be established in two ways. Firstly, each kidney should be measured by a common duplex ultrasound measurement to assess the resistance index (RI) in the three poles of the kidney (upper, middle, lower pole). Secondly, intraoperative fluorescence angiography is going to be performed. Therefore, the camera of the fluorescence angiography system (SPY Elite System, Novadaq, USA) is positioned over the organ, and the fluorescence dye (ICG) is applicated intravenously. The aim will be to correlate the fluorescence angiography findings with the RIs and therefore to establish valuable fluorescence parameters.

Conditions

• Kidney Transplantation

Interventions

Type	Name	Description
DRUG	Indocyanine green	perioperative application of Indocyanine green (ICG)

Timeline

• Start date: 2016-04-01
• Primary completion: 2018-12-01
• Completion: 2019-01-01
• First posted: 2016-05-18
• Last updated: 2020-05-08

Locations

2 sites across 1 country: Germany