NCT02773758

Study to Investigate the Efficacy of an Occluding Dentifrice in Providing Relief From Dentine Hypersensitivity

Short Term Clinical Study Investigating the Efficacy of an Occluding Dentifrice in Providing Relief From Dentinal Hypersensitivity

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 143 (actual)
• Sponsor: GlaxoSmithKline · Industry
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Accepted

Summary

This will be a single centre, two week, randomised, examiner blind, two treatment arm, parallel design, stratified (by maximum baseline Schiff sensitivity score of the two selected test teeth), controlled study, in participant with at least two sensitive teeth that meet the study criteria at the Screening and Baseline visits. The study will be conducted in participants in good general health, with pre-existing self-reported and clinically diagnosed tooth sensitivity at screening.

Conditions

• Dentin Sensitivity

Interventions

Type	Name	Description
OTHER	Stannous Fluoride Dentifrice	Experimental dentifrice containing 0.454%w/w stannous fluoride (1100ppm fluoride)
OTHER	Sodium monofluorophosphate Dentifrice	Dentifrice containing 0.76% w/w sodium monofluorophosphate (1000ppm fluoride)

Timeline

• Start date: 2016-01-01
• Primary completion: 2016-03-11
• Completion: 2016-03-11
• First posted: 2016-05-16
• Last updated: 2017-09-29
• Results posted: 2016-12-12

Locations

1 site across 1 country: Canada