NCT02772302

Feasibility of mindBEAGLE in Disorders of Consciousness or Locked-In Syndrome

Feasibility Study of the mindBEAGLE Device in Patients With Disorders of Consciousness or Locked-In Syndrome

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 20 (actual)
• Sponsor: Massachusetts General Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The primary aims of this study are: 1. To determine the feasibility of deploying mindBEAGLE, a portable, bedside EEG-based system, in the Intensive Care Unit in patients with disorders of consciousness (DOC) or locked-in syndrome (LIS); 2. To determine if mindBEAGLE neurophysiologic markers of cognitive function correlate with bedside behavioral assessments of consciousness; 3. To determine if mindBEAGLE neurophysiologic markers of cognitive function correlate with functional MRI (fMRI) and electroencephalography (EEG) biomarkers of consciousness; 4. To determine if mindBEAGLE can serve as an assistive communication device for people with LIS.

Detailed description

1. To determine the feasibility of deploying mindBEAGLE, a portable, bedside EEG-based system, in the Neurosciences Intensive Care Unit in patients with DOC or LIS; 2. To determine if mindBEAGLE neurophysiologic markers of cognitive function correlate with bedside behavioral assessments of consciousness; 3. To determine if mindBEAGLE can serve as an assistive communication device for people with LIS.

Conditions

• Consciousness Disorders
• Locked-In Syndrome

Interventions

Type	Name	Description
DEVICE	mindBEAGLE EEG-based brain-computer interface

Timeline

• Start date: 2016-03-01
• Primary completion: 2019-12-01
• Completion: 2019-12-17
• First posted: 2016-05-13
• Last updated: 2021-06-03
• Results posted: 2021-04-30

Locations

1 site across 1 country: United States