Clinical Trials Directory

Trials / Completed

CompletedNCT02771340

Study Evaluating Single and Repeated Intravitreal Doses of ICON-1 in Patients With Uveal Melanoma

A Phase 1, Open-label, Multicenter Study Evaluating the Safety and Tolerability, Biologic Activity, Pharmacodynamics, and Pharmacokinetics of Single and Repeated Escalating Intravitreal Doses of ICON-1 in Patients With Uveal Melanoma Who Are Planned to Undergo Enucleation or Brachytherapy

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
10 (actual)
Sponsor
Iconic Therapeutics, Inc. · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to evaluate the safety, tolerability, biological activity, pharmacokinetics and pharmacodynamic activity of single and repeated escalating intravitreal doses of ICON-1 in patients with primary uveal melanoma who are planned to undergo enucleation or brachytherapy of the affected eye.

Conditions

Interventions

TypeNameDescription
BIOLOGICALICON-1Intravitreal injection of ICON-1

Timeline

Start date
2016-05-01
Primary completion
2017-09-01
Completion
2017-09-01
First posted
2016-05-13
Last updated
2020-10-01
Results posted
2020-09-14

Locations

8 sites across 1 country: United States

Source: ClinicalTrials.gov record NCT02771340. Inclusion in this directory is not an endorsement.