NCT02771002

Assessment of Peripheral Perfusion in the Critically Ill Patient

Evaluation of the Clinical Assessment of Peripheral Perfusion by Capillary Refill Time and Peripheral Perfusion Index

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 100 (actual)
• Sponsor: Insel Gruppe AG, University Hospital Bern · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to evaluate PPI as a surrogate for clinical signs of peripheral perfusion in patients in septic shock and after cardiac surgery.

Detailed description

The aim of this study is to validate PPI as a continuous, objective measurement of peripheral perfusion indicated by clinical sings of tissue perfusion in patients with septic shock. Furthermore, PPI shall be compared to the perfusion of solid organs evaluated by ultrasound of liver, kidney and gut. In a group of healthy volunteers the investigators will determine normal values in ambient temperature and after cooling of an extremity. Another group of patients after cardiac surgery, where usually a poor tissue perfusion without metabolic failure is present will serve as another "control" population in their post-surgery stabilization period. The values from healthy volunteers and cardiac surgery patients will be compared to those of patients in septic shock.

Conditions

• Peripheral Perfusion

Interventions

Type	Name	Description
DEVICE	Peripheral Perfusion index by Carescape Patientenmonitor	Peripheral Perfusion index measured with pulse-oximetry by Carescape Patientenmonitor

Timeline

• Start date: 2016-07-13
• Primary completion: 2017-03-28
• Completion: 2017-03-28
• First posted: 2016-05-12
• Last updated: 2017-06-22

Locations

1 site across 1 country: Switzerland