NCT02770235

Evaluation of Advanced Glycation End-products (AGE) and the Erectile Dysfunction (DE) in Diabetic Patients

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 97 (actual)
• Sponsor: Centre Hospitalier Universitaire, Amiens · Academic / Other
• Sex: Male
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

In diabetics there is an abnormally increased production of AGEs due to hyperglycemia. An association was shown between AGE measured by biopsy (invasive) and DE patients with diabetes (increase of AGE level in the corpora cavernosa). To date no studies have explored the link between DE and the measure of AGE by a non-invasive method of Auto-fluorescence (AF) Skin (AGEReaderTM). If the hypothesis of an association between DE and AGE measured by AF was checked, screening for erectile dysfunction and measurement of AGEs could help to improve the overall management of diabetic patient (including cardiovascular) and their quality of life.

Conditions

• Diabetes Mellitus, Non-Insulin-Dependent
• Erectile Dysfunction

Interventions

Type	Name	Description
OTHER	DE assessment	by a validated self-administered questionnaire: Index International erectile function (IIEF-15)
OTHER	AGE measurement	By AGE-ReaderTM

Timeline

• Start date: 2014-03-17
• Primary completion: 2019-03-16
• Completion: 2019-03-16
• First posted: 2016-05-12
• Last updated: 2025-09-19

Locations

1 site across 1 country: France