NCT02767635

Comparison Between Steroid and Different Sites of Botulinum Toxin Injection in the Treatment of Lateral Epicondylalgia

Comparison Between Steroid and Two Different Sites of Botulinum Toxin Injection in the Treatment of Lateral Epicondylalgia: A Randomized Double-blind Active Drug-controlled Pilot Study

• Status: Unknown
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 90 (estimated)
• Sponsor: National Cheng-Kung University Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

The aim of the study is to compare two different injection sites of low dose botulinum toxin type A with steroid in treating lateral epicondylalgia.

Detailed description

Lateral epicondylalgia or tennis elbow is a common painful elbow disorder with a prevalence of 1% to 3% in the general population and has a higher rate up to 14.5% in strenuous jobs. Botulinum toxin type A injection was an emerging option in treating lateral epicondylalgia. In this study, the patients were randomly assigned into three groups: 1. Botox-Epic group received 20 units of Botox injection into lateral epicondyle; 2. Botox-Tend group had 20 units of Botox injected into tender point of muscles; 3. Steroid group had 40mg of triamcinolone injected into lateral epicondyle. The aim of this randomized controlled study was to compare the effects of injection with corticosteroid and botulinum toxin type A via two different sites in patients with lateral epicondylalgia.

Conditions

• Tennis Elbow

Interventions

Type	Name	Description
DRUG	Botox-Epic	injected 20 units of Botox into lateral epicondyle in Botox-Epic group
DRUG	Botox-Tend	injected 20 units of Botox into tender point of muscles in Botox-Tend group
DRUG	triamcinolone acetonide (Steroid)	injected 40mg of triamcinolone acetonide into lateral epicondyle in Steroid group

Timeline

• Start date: 2012-01-01
• Primary completion: 2016-12-01
• Completion: 2016-12-01
• First posted: 2016-05-10
• Last updated: 2016-05-10

Locations

1 site across 1 country: Taiwan