NCT02767284

A Comparative Study of Six Methods to Measure Human Contrast Vision

UCST Studie 1 - Jämförande Studie Mellan några Befintliga Och Nyutvecklade Metoder för Att mäta Den Spektrala kontrastkänslighetsfunktionen Hos människa

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (estimated)
• Sponsor: Uppsala University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

This study evaluates the relative performance of different methods to measure the human spectral contrast sensitivity function (CSF).

Detailed description

The human spectral contrast sensitivity function (CSF) is a better way to estimate human vision than letter charts commonly used by ophthalmologists, optometrists and opticians. The current methods used to measure the CSF are often unreliable, due to high variability between measurements. This study will compare four (4) new tests with two (2) currently used standard tests. The contrast sensitivity function will be measured using all of the six (6) methods three times (3) in each of the two (2) eyes at two (2) occasions. Each subjects CSF will be measured 6x3x2x2 = 72 times. In addition, for each of the CSF measurements, the time used to measure the CSF and number of background variables for the subjects will be recorded. After informed consent is obtained, the subjects will undergo a visual examination. If they match the inclusion criteria they will be included. At that time or at their earliest possible convenience, their CSF will be measured using the six methods and some background information will be recorded. The follow-up measurement occasion will occur between 4 to 6 weeks (28 to 42 days) after the first. To facilitate comparison with previous studies, the CSF-measurements (in rel. contrast/cycles/degree) will be converted to a log (Base 10 logarithm) scale. The unit will thus be log CSF (LCSF) \[log\[relative contrast\]/log\[cycles/per degree\]\].

Conditions

• Methods to Measure Contrast Vision

Interventions

Type	Name	Description
DEVICE	UCST-V1	A previously developed device, Uppsala Contrast Sensitivity Tester - UCST-V1, that quickly measures the human CSF in one stimulus.
DEVICE	UCST-V2	A refined version of the UCST-V1 that randomizes frequency order.
DEVICE	UCST-V3	A version that utilises eye-tracking technology to make the measurements more accurate.
DEVICE	Quick-CSF (QCSF)	A fast contrast sensitivity measurement method using a Bayesian algorithm.
DEVICE	Pelli-Robson	A standard method developed using a Sloan-letter chart with decreasing contrast.
DEVICE	Optec 6500	A standard test using sinusoidal gratings to measure the contrast sensitivity function.

Timeline

• Start date: 2016-06-01
• Primary completion: 2017-06-01
• Completion: 2017-10-01
• First posted: 2016-05-10
• Last updated: 2016-06-28

Locations

1 site across 1 country: Sweden