NCT02765828

Identification of Tongue Involvement in Late-Onset Pompe Disease

Determining the Diagnostic Utility of the Identification of Tongue Involvement in Late-Onset Pompe Disease (LOPD)

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 73 (actual)
• Sponsor: Duke University · Academic / Other
• Sex: All
• Age: 12 Years
• Healthy volunteers: Not accepted

Summary

This purpose of this study is to determine if tongue strength and tongue ultrasound measurements differentiates patients with untreated late-onset Pompe Disease (LOPD) from patients with acquires/hereditary myopathies or neuropathies. It is hypothesized that abnormalities in tongue function and structure in patients with LOPD may be useful in discriminating this condition from others that have similar presentations.

Conditions

• Myopathy
• Neuropathy
• Glycogen Storage Disease Type II (Late-onset Pompe Disease)

Interventions

Type	Name	Description
OTHER	Observational study	The following exams will be done in all cohorts: tongue manual muscle testing (MMT), tongue quantitative muscle testing, tongue ultrasound measurements

Timeline

• Start date: 2016-05-25
• Primary completion: 2019-07-15
• Completion: 2019-07-15
• First posted: 2016-05-09
• Last updated: 2021-07-06

Locations

1 site across 1 country: United States