NCT02763280

Efficacy and Safety of Ginseng Extract on Improvement of Bone Metabolism in Menopausal Women

A 12-week, Randomized, Double-blind, Placebo-controlled Human Trial to Evaluate the Efficacy and Safety of Ginseng Extract on Improvement of Bone Metabolism in Menopausal Women

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 90 (actual)
• Sponsor: Chonbuk National University Hospital · Academic / Other
• Sex: Female
• Age: 40 Years
• Healthy volunteers: Accepted

Summary

Recently, osteoporosis has been recognized as a serious health problem in the elderly, it has also increased in young • middle-aged layer. Ginseng is history 2, 000 years Korean typical herbal medicine which is used as a medicinal is known the mystery of Elixir from a long time ago. A previous study was administered ginseng extract results in animal models induced osteoporosis, the bone-related biomarkers, including improved bone density and bone mass.

Detailed description

The investigators performed a 12-week, randomized, double-blind, placebo-controlled human trial to evaluate the efficacy and safety of ginseng extract on improvement of Bone metabolism in menopausal women. The investigators measured Serum Osteocalcin, Urinary Deoxypyridinoline, DPD/OC ratio, Serum CTX, NTX, Ca, Phosphorus, BSALP(vone specific-alkaline phosphatase), P1NP(Procollagen type 1 N-terminal propeptide), WOMAC index(Western Ontario and McMaster Universities Arthritis).

Conditions

• Osteopenia

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Ginseng extract 1g	Ginseng extract 1g, parallel design
DIETARY_SUPPLEMENT	Ginseng extract 3g	Ginseng extract 3g, parallel design
DIETARY_SUPPLEMENT	Placebo	placebo, parallel design

Timeline

• Start date: 2015-06-01
• Primary completion: 2015-07-01
• Completion: 2016-09-01
• First posted: 2016-05-05
• Last updated: 2018-02-05

Locations

1 site across 1 country: South Korea