NCT02762968

The Effects of Probiotic and HMB Supplementation on Immune and Digestive Function in Special Operations Soldiers

The Effects of 8-weeks of Probiotic and HMB Supplementation on Immune and Digestive Function in Special Operations Soldiers

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 26 (actual)
• Sponsor: Metabolic Technologies Inc. · Industry
• Sex: All
• Age: 18 Years – 30 Years
• Healthy volunteers: Accepted

Summary

The study will determine whether acute ingestion of a probiotic combined with beta-hydroxy-beta-methylbutyrate (HMB) can enhance immune and digestive function in soldiers during 8-weeks of advanced infantry training.

Detailed description

Up to sixty soldiers from an elite infantry unit will perform a parallel design investigation. Soldiers will be randomly assigned to one of four groups. Group 1 will consume the probiotic plus HMB, group 2 will consume HMB only, group 3 will consume only the probiotic, and group 4 will consume only placebo. All four groups will be garrisoned together, eat the same meals, and perform the same activity. All groups will be tested before as well as after an 8-week advanced infantry training program. During each testing session resting blood samples will be obtained to assess cytokine, inflammatory, and muscle damage markers. Additionally, questionnaires will be used to determine digestive health. Anthropometric, performance, and muscle volume measures will also be assessed prior to and immediately following the supplementation and training protocol.

Conditions

• Military Training

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Placebo	Placebo capsules similar to the experimental treatments.
DIETARY_SUPPLEMENT	HMB	Capsules containing calcium HMB.
DIETARY_SUPPLEMENT	BC30	Bacillus Coagulans GBI-30, 6086 (BC30) mixed in water.

Timeline

• Start date: 2016-04-01
• Primary completion: 2016-07-01
• Completion: 2016-08-01
• First posted: 2016-05-05
• Last updated: 2017-01-30

Locations

1 site across 1 country: Israel