NCT02760160

Dietary Prevention of Photodamage in Skin With Grapes

Dietary Prevention of Photodamage in Skin With Grapes: A Human Clinical Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 18 (actual)
• Sponsor: University of Alabama at Birmingham · Academic / Other
• Sex: All
• Age: 18 Years – 99 Years
• Healthy volunteers: Accepted

Summary

To assess the effect of orally administered grape powder on the sunburn reaction in humans.

Detailed description

To determine whether oral grape powder will result in a reduction in biomarkers associated with basal cell carcinomas (BCCs) and squamous cell carcinomas (SCCs). Biomarkers taken from non-sun-exposed skin and UV-exposed skin before and after treatment will be compared. The ultimate goal of this study will be to generate new knowledge of the photoprotective effect of grape powder on UV exposure. The results may be employed as the basis for a larger clinical trial to evaluate the potential of grapes to prevent non-melanoma skin cancers (NMSCs) and sun damage.

Conditions

• Non-melanoma Skin Cancer

Interventions

Type	Name	Description
OTHER	Reconstituted grape powder	To prevent UV-induced skin cancers. Each subject's will have one arm exposed to 6 separate doses of UV (J/m2) \[114, 217, 343, 500, 619, 848\].

Timeline

• Start date: 2015-10-01
• Primary completion: 2018-09-27
• Completion: 2018-09-27
• First posted: 2016-05-03
• Last updated: 2019-03-08

Locations

1 site across 1 country: United States