Trials / Completed
CompletedNCT02756741
Comparison of Standard Dose Versus Once a Day Intravenous Albumin in Spontaneous Bacterial Peritonitis
Assessment of Cytokine Profile in an Open Labeled Randomized Controlled Trial of Standard Dose vs. Once a Day Intravenous Albumin in Patients With Spontaneous Bacterial Peritonitis
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 40 (actual)
- Sponsor
- All India Institute of Medical Sciences · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The standard recommended management of spontaneous bacterial peritonitis (SBP) includes a third-generation cephalosporin (cefotaxime or ceftriaxone) and high dose albumin (1.5g/kg on day 1 and 1g/kg on day 3). The major drawback of the current recommendations is the high price of albumin. In the current randomized control trial investigators compared the effect of standard recommended dose of albumin (1.5g/kg on day 1 and 1g/kg on day 3) vs. low dose (20g/d for 5 days) on the resolution of SBP and subsequent cytokine changes in ascitic fluid and blood.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | ALBUMIN | Albumin in two different doses |
Timeline
- Start date
- 2014-04-01
- Primary completion
- 2015-07-01
- Completion
- 2015-07-01
- First posted
- 2016-04-29
- Last updated
- 2016-04-29
Source: ClinicalTrials.gov record NCT02756741. Inclusion in this directory is not an endorsement.