NCT02756598

Stress, Anxiety and Type A Personality and Analgesics

Stress, Anxiety and Type A Personality and Analgesics. Impact on Induction Time and Consumption of Analgesics During Cardiac Surgery

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: Aarhus University Hospital · Academic / Other
• Sex: —
• Age: 16 Years – 90 Years
• Healthy volunteers: Not accepted

Summary

Patients scheduled for elective cardiac surgery are preoperative evaluated using different personality type, stress and anxiety tests. Patient are randomized to receive the investigators' standard moderate dose sufentanil (bolus 1microgram/kg and propofol 0.03 mg/kg/min) or low dose sufentanil (bolus 0.5 microgram/kg and propofol 0.06 mg/kg/min).

Detailed description

Patients randomized and the type of induction informed to the anaesthetist 30 minutes before surgery. Patients are monitored before induction of anesthesia. Propofol is started on the randomized infusion rate. Sufentanil bolus are given according to randomization. BIS level is followed. Time to reach BIS \< 50 is monitored. BIS after 30, 60 and 90 minutes are registered. Lowest BIS during surgery are registered. Total amounts of sufentanil and propofol recorded.

Conditions

• Postoperative; Dysfunction Following Cardiac Surgery

Interventions

Type	Name	Description
DRUG	Sufentanil I	bolus dose of sufentanil 1 microgram/kg
DRUG	Sufentanil II	bolus dose of sufentanil 0.5 microgram/kg
DRUG	Propofol I	Continued dose of propofol 0.03 mg/kg/min
DRUG	Propofol II	Continued dose of propofol 0.06 mg/kg/min

Timeline

• Start date: 2015-01-01
• Primary completion: 2018-01-01
• Completion: 2018-06-30
• First posted: 2016-04-29
• Last updated: 2019-07-10