NCT02756468

Procalcitonin Reveals Early Dehiscence in Pancreatic Surgery: the PREDIPS Study

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 100 (estimated)
• Sponsor: University of Roma La Sapienza · Academic / Other
• Sex: All
• Age: 18 Years – 100 Years
• Healthy volunteers: Not accepted

Summary

Background. Pancreatic cancer surgery is associated with very high risk of postoperative morbidity and mortality. Anastomotic leak (AL) is one of the worst complications associated with relevant short and long-term sequelae. Procalcitonin (PCT) is a biomarker used to monitor bacterial infections and guide antibiotic therapy and has been shown to have better predictive value of AL after colorectal surgery than C-reactive protein (CRP) and white blood cell count (WBC). Purpose. The investigators designed a monocentric pilot study to test if PCT might be a sensitive and reliable marker of AL after pancreatic surgery

Conditions

• Pancreatic Cancer

Interventions

Type	Name	Description
OTHER	pts operated for pancreatic cancer	measuring CRP and PCT in 3rd and 5th POD after pancreatic cancer resection

Timeline

• Start date: 2015-01-01
• Primary completion: 2016-06-01
• Completion: 2016-12-01
• First posted: 2016-04-29
• Last updated: 2016-04-29

Locations

1 site across 1 country: Italy