NCT02756455

Procalcitonin Reveals Early Dehiscence in Gastric Surgery: the PREDIGS Study

Procalcitonin Reveals Early Dehiscence In Gastric Surgery: the PREDIGS Study

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 100 (estimated)
• Sponsor: University of Roma La Sapienza · Academic / Other
• Sex: All
• Age: 18 Years – 100 Years
• Healthy volunteers: Not accepted

Summary

Background. Gastric cancer surgery is associated with high risk for postoperative morbidity and mortality. Anastomotic leak (AL) is one of the worst complications associated with relevant short and long-term sequelae. Procalcitonin (PCT) is a biomarker used to monitor bacterial infections and guide antibiotic therapy and has been shown to have better predictive value of AL after colorectal surgery than C-reactive protein (CRP) and white blood cell count (WBC). Purpose. Investigators designed a monocentric pilot study to test if PCT might be a sensitive and reliable marker of AL after gastric surgery

Conditions

• Gastric Cancer

Interventions

Type	Name	Description
OTHER	gastric cancer pts undergoing surgery	Measure PCT (procalcitonin), CRP (C-reactive protein) and WBC (white blood cell count) in 3rd and 5th postoperative day and registration of all intra and postoperative complications

Timeline

• Start date: 2015-01-01
• Primary completion: 2016-06-01
• Completion: 2016-12-01
• First posted: 2016-04-29
• Last updated: 2016-04-29

Locations

1 site across 1 country: Italy