NCT02756312

The Impact of Anesthesia on High- Grade Glioma Patients

The Impact of Anesthesia on the Outcome of Supratentorial High- Grade Glioma Patients After Craniotomy

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 196 (estimated)
• Sponsor: Beijing Tiantan Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

Although bench data and retrospective studies have provided a promising picture of the possible influence of anesthetic technique on the risk of tumor progression and patients mortality, current evidence from RCTs is inadequate to show whether the type of anesthetics might influence tumor progression and patient survival.There are many thousands of patients with a cancer diagnosis undergoing surgery every year, and in the context of biological plausibility, it should lead to the urgent undertaking of RCTs to further evaluate the association between the anesthetic management and patient outcome.

Detailed description

Although bench data and retrospective studies have provided a promising picture of the possible influence of anesthetic technique on the risk of tumor progression and patient mortality, current evidence from RCTs is inadequate to show whether the type of anesthetics might influence the outcome of the patients.There are many thousands of patients with a cancer diagnosis undergoing surgery every year, and in the context of biological plausibility, it should lead to the urgent undertaking of RCTs to further evaluate the association between the anesthetic management and patient outcome.

Conditions

• Anesthesia, Outcome, High-grade Glioma

Interventions

Type	Name	Description
OTHER	IV Anesthesia	The patients will receive intravenous anesthesia
OTHER	IH anesthesia	The patients will receive inhalation anesthesia

Timeline

• Start date: 2020-10-01
• Primary completion: 2022-12-31
• Completion: 2022-12-31
• First posted: 2016-04-29
• Last updated: 2020-09-09

Locations

1 site across 1 country: China