NCT02753075

A Study in Dentinal Hypersensitivity (DH) Participants to Assess the Efficacy of an Occluding Dentifrice.

A Clinical Study Investigating the Efficacy of Two Experimental Oral Rinses in Providing Long Term Relief From Dentinal Hypersensitivity

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 240 (actual)
• Sponsor: GlaxoSmithKline · Industry
• Sex: All
• Age: 18 Years – 55 Years
• Healthy volunteers: Accepted

Summary

This study will investigate the longitudinal efficacy of two experimental oral rinses, one containing 1.5% weight/weight (w/w) dipotassium oxalate monohydride (KOX) /0 Parts per Million (ppm fluoride) and the other 2.0% w/w KOX /45ppm fluoride, for the relief of dentinal hypersensitivity (DH), compared to a placebo oral rinse, when used as an adjunct to twice daily brushing with a standard fluoride toothpaste.

Conditions

• Dentin Sensitivity

Interventions

Type	Name	Description
DEVICE	Experimental Oral Rinse 1	Oral rinse containing 1.5% w/w KOX, 0ppm F, pH 4.5
DEVICE	Experimental Oral Rinse 2	Oral rinse containing 2.0% w/w KOX, 45ppm F, pH 4.5
OTHER	Placebo Oral Rinse	Oral rinse containing 0% w/w KOX 0ppm F, pH 4.5
DRUG	Fluoride toothpaste	Oral rinse containing 1000ppm fluoride as sodium monofluorophosphate

Timeline

• Start date: 2015-09-08
• Primary completion: 2015-12-01
• Completion: 2015-12-18
• First posted: 2016-04-27
• Last updated: 2018-08-27
• Results posted: 2017-03-06

Locations

1 site across 1 country: United States