NCT02750696

Comparison of Two Combinations of Opioid and Non-opioid Analgesics for Acute Periradicular Abscess

Comparison of Two Combinations of Opioid and Non-opioid Analgesics for Acute Periradicular Abscess: A Randomized Clinical Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 27 (actual)
• Sponsor: Federal University of Rio Grande do Sul · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Aim: The aim of this study was to compare the analgesic efficacy of two combinations of opioid and non-opioid analgesics for acute periradicular abscesses. Methodology: This study included 24 patients who sought emergency care in a Brazilian dental school. The patients were randomly divided into two groups: Codeine/Acetaminophen - oral prescription of codeine (30 mg) plus acetaminophen (500 mg), every 4 h, for 3 days or Tramadol/Acetaminophen - oral prescription of tramadol hydrochloride (37.5 mg) plus acetaminophen (500 mg) on the same schedule. Patients recorded pain scores in a pain diary 6, 12, 24, 48, and 72 h after treatment, using the Visual Analogue Scale.

Conditions

• Periapical Abscess

Interventions

Type	Name	Description
DRUG	Fixed-dose oral tablet of codeine/ acetaminophen every 4 hours for 3 days	Patients in this group received opioid/ non-opioid analgesic combination.
DRUG	Fixed-dose oral tablet of tramadol/ acetaminophen every 4 hours for 3 days	Patients in this group received opioid/ non-opioid analgesic combination.

Timeline

• Start date: 2013-04-01
• Primary completion: 2014-12-01
• Completion: 2015-04-01
• First posted: 2016-04-25
• Last updated: 2016-04-25