NCT02745899

The Effect of Cow Milk Consumption on Respiratory Symptoms and Pulmonary Functions in Asthmatic and Non Asthmatic Children

The Effect of Cow-milk Consumption on Respiratory Symptoms and Pulmonary Functions in Asthmatic and Non-asthmatic Children

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 100 (estimated)
• Sponsor: Tel-Aviv Sourasky Medical Center · Other Government
• Sex: All
• Age: 6 Years – 18 Years
• Healthy volunteers: Accepted

Summary

the investigators hypothesis is that milk consumption, either in the acute phase and through prolonged exposure, does not cause or increase respiratory symptoms or airway inflammation. the investigators aim to objectively prove this by examining respiratory symptoms and signs and objectively measuring parameters of airway inflammation and hyper responsiveness after consumption of cow milk or soy milk substitute.

Detailed description

In this prospective single blinded placebo controlled trial, acute milk consumption will be evaluated. 50 asthmatic and 50 healthy children aged 6-18 will drink 240 ml of cow milk or soy milk substitute. Respiratory symptoms by questionnaire and physical examination will be evaluated. Airway response and inflammation will be assessed by fraction of exhaled Nitric Oxide (FENO) and spirometry before and after the exposure.

Conditions

• Asthma

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Cow milk	Ingestion of 240 ml cow milk
DIETARY_SUPPLEMENT	Soy milk	Ingestion of 240 ml soy milk

Timeline

• Start date: 2016-05-01
• Primary completion: 2017-05-01
• Completion: 2017-05-01
• First posted: 2016-04-20
• Last updated: 2016-05-03