NCT02745028

Monosodium Glutamate on Gastric Emptying

Effect of a Single Dose of Monosodium Glutamate on Delayed Gastric Emptying in Children

• Status: Withdrawn
• Phase: N/A
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: Veronica Beatriz Busoni · Academic / Other
• Sex: All
• Age: 12 Months – 17 Years
• Healthy volunteers: Not accepted

Summary

Children with a radionuclide gastric emptying test with abnormal results will undergo a second test with the addition of a weight adjusted dose of monosodium glutamate. The purpose of the study is to determine if a single dose of monosodium glutamate can shorten the gastric emptying time.

Detailed description

There is evidence that monosodium glutamate has effects on synapsis at the gastric and duodenum level that results in stimulation of contractility resulting on increase rate of gastric emptying. The purpose of the study is to demonstrate that the administration of a single dose of monosodium glutamate can shorten the gastric emptying time. Patients with a prior study indicating a delay of gastric empting time, will undergo a second test with the addition of a weight adjusted dose of monosodium glutamate. Each patient will serve as her/his own control. Results will be analysed by pair-T test.

Conditions

• Delayed Gastric Emptying

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Monosodium glutamate	A single dose of weight adjusted monosodium glutamate will be added at the time of a repeat radionuclide gastric emptying study

Timeline

• Start date: 2016-04-01
• Primary completion: 2017-10-01
• Completion: 2017-10-01
• First posted: 2016-04-20
• Last updated: 2023-03-02