Trials / Completed
CompletedNCT02744508
Comparison of Palonosetron Versus Combination of Palonosetron and Dexamethasone for Preventing Postoperative Vomiting in Patients Receiving Fentanyl by Patient-controlled Analgesia After Minor Orthopedic Surgery
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 202 (actual)
- Sponsor
- Yonsei University · Academic / Other
- Sex
- All
- Age
- 20 Years – 65 Years
- Healthy volunteers
- Not accepted
Summary
Postoperative nausea and vomiting (PONV) is related with extended hospital day and risk factor of aspiration pneumonia. Postoperative patient controlled intravenous analgesia is related with postoperative nausea and vomiting. Selective 5-HT3 antagonist, Palonosetron, is the most recent medication for prevention of PONV. Purpose of our study is comparison of PONV preventive effect of palonosetron and combination of palonosetron and dexamethasone.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | palonosetron | |
| DRUG | palonosetron with dexamethasone |
Timeline
- Start date
- 2015-07-24
- Primary completion
- 2017-03-20
- Completion
- 2017-03-20
- First posted
- 2016-04-20
- Last updated
- 2018-06-20
Locations
1 site across 1 country: South Korea
Source: ClinicalTrials.gov record NCT02744508. Inclusion in this directory is not an endorsement.