NCT02743624

Criteria Analysis for Ventilatory Support Adjustment of Mechanical Ventilation

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 27 (actual)
• Sponsor: University of Sao Paulo General Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 90 Years
• Healthy volunteers: Not accepted

Summary

The indications for mechanical ventilation (MV) include excessive work of breathing, with or without evidence of respiratory muscle fatigue. The setting of the MV is still a challenge because it is based on criteria understudied, often subjective and observer-dependent. Despite several studies, to our knowledge has never been done before is the precise definition of the optimal range of ventilatory support. Novel and recognizable diagnostic techniques will be applied. No single parameter of the breathing pattern has good accuracy for the adjustment of ventilatory support. Non-invasive measures such as P0.1 and rate of muscle relaxation may have good accuracy for the adjustment of ventilatory support.

Detailed description

Use of excessive pressure support

Conditions

• Acute Mechanical Ventilatory Failure

Interventions

Type	Name	Description
PROCEDURE	Variation of the level of pressure support during the mechanical ventilation	The pressure support of the patient was changed form the baseline to 20 cmH20 and then stepwise decreased to 2 cmH20,

Timeline

• Start date: 2016-02-01
• Primary completion: 2016-11-01
• Completion: 2016-12-01
• First posted: 2016-04-19
• Last updated: 2017-01-19

Locations

2 sites across 1 country: Brazil