NCT02743091

Idiopathic Pre-capillary Pulmonary Hypertension in ESKD Patients

Idiopathic Pre-capillary Pulmonary Hypertension in Patients With End-stage Kidney Disease

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 1,988 (actual)
• Sponsor: Toujinkai Hospital · Academic / Other
• Sex: All
• Age: 50 Years – 85 Years
• Healthy volunteers: Not accepted

Summary

This study investigates the prevalence and prognosis of idiopathic pre-capillary pulmonary hypertension (PH) in patients with end-stage kidney disease (ESKD).

Detailed description

Pulmonary hypertension (PH) is a rare cardiovascular disease with progressive and fatal features. PH is classified into the 5 groups, and the prevalence of group 1 pulmonary arterial hypertension, including idiopathic and heritable, is 5 to 15 cases per one million adults and a median survival was reportedly three years. PH found in patients with end-stage kidney disease (ESKD) is classified into group 5, because the pathogenesis and clinical characteristics have not been clarified. The prevalence of PH in patients with ESKD was reportedly around 17\~56% based on echocardiographic studies. In this study, we evaluated the incidence of idiopathic pre-capillary PH of ESKD patients by right heart catheterization, and examined the prognosis by following the occurrence of heart failure death.

Conditions

• Pulmonary Hypertension

Timeline

• Start date: 2001-01-01
• Primary completion: 2015-12-01
• Completion: 2015-12-01
• First posted: 2016-04-19
• Last updated: 2016-04-19