NCT02741882

Zika and Microcephaly: Case-control Study

Rash Accompanied by Three or More Dengue-like Symptoms During Pregnancy and Microcephaly: Case-control Study

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 110 (actual)
• Sponsor: Laboratório Sabin · Industry
• Sex: Female
• Age: 16 Years
• Healthy volunteers: Accepted

Summary

It is suspected that zika virus infection during pregnancy is associated with microcephaly. The objective of this study is to investigate the occurrence of rash accompanied by three or more dengue-like signs and symptoms during pregnancy is related to the microcephaly using the case-control design.

Detailed description

The investigators will carry out a case-control study among mothers who delivered their babies at Nossa Senhora de Lourdes maternity hospital located in Aracaju, state of Sergipe, Brazil from September 1, 2015 through January 5, 2016. Data sources for the phase I of the study will consist of medical records review and a standard questionnaire applied by telephone to collect information about demographic features, clinical signs and symptoms, and the duration and severity of the illness. Phase II will include dengue, chikungunya and dengue serologic test results as secondary outcome, if available. The objective of this study is to investigate the occurrence of rash accompanied by three or more dengue-like signs and symptoms during pregnancy is related to the microcephaly using the case-control design

Conditions

• Microcephaly

Interventions

Type	Name	Description
OTHER	Questionary	Questionary with clinical, demographic and behavior outcomes at the pregnancy period

Timeline

• Start date: 2016-02-01
• Primary completion: 2016-08-01
• Completion: 2017-02-01
• First posted: 2016-04-18
• Last updated: 2017-02-23

Locations

1 site across 1 country: Brazil