NCT02740933

Demeclocycline Fluorescence for Intraoperative Delineation Brain Tumors

• Status: Unknown
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 40 (estimated)
• Sponsor: Massachusetts General Hospital · Academic / Other
• Sex: All
• Age: 21 Years
• Healthy volunteers: Not accepted

Summary

This research study is studying a drug called Demeclocycline that may help brain surgeons see tumors with a microscope during surgery.

Detailed description

This research study is a Feasibility Study, which is the first time investigators are examining this study intervention.The FDA (the U.S. Food and Drug Administration) has not approved Demeclocycline for your specific disease but it has been approved for other uses. In this research study, the investigators would like to determine the lowest dose of Demeclocycline that will allow surgeons to detect tumor cells during surgery. These cells will be marked through a process called fluorescence, which will cause tumor cells to glow brightly on an image in comparison to its surroundings.

Conditions

• Brain Tumor

Interventions

Type	Name	Description
DRUG	Demeclocycline

Timeline

• Start date: 2016-04-01
• Primary completion: 2019-01-01
• Completion: 2021-01-01
• First posted: 2016-04-15
• Last updated: 2016-04-15

Locations

1 site across 1 country: United States