NCT02740140

Epidemiology of H. Pylori Transmission

Epidemiology of H. Pylori Transmission and Immunoepidemiology of Concomitant Infections

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 1,750 (actual)
• Sponsor: Stanford University · Academic / Other
• Sex: All
• Age: 18 Years – 55 Years
• Healthy volunteers: Accepted

Summary

This observational epidemiologic study with nested cross-sectional and longitudinal aims will evaluate host immune response to mixed chronic infections (Helicobacter pylori, latent tuberculosis, intestinal helminthiasis) in recent US immigrants.

Detailed description

1750 clinically-well, adult (age 18-55 years), recent immigrants (\<2 years U.S. residence), referred through cooperating public health clinics in the Santa Clara Valley area, CA will be screened for H. pylori, helminth, and latent tuberculosis infections \["Screening" population\]. Of these 1750, 426 will be selected for more intensive study (Cohort population), 105 of whom will receive baseline endoscopy. Of those selected for the cohort, 300 are expected to complete a 9-month follow-up assessment, 75 of whom are expected to undergo a second follow-up endoscopy.

Conditions

• Communicable Diseases

Timeline

• Start date: 2008-06-01
• Primary completion: 2011-06-01
• Completion: 2013-07-01
• First posted: 2016-04-15
• Last updated: 2016-04-15

Locations

2 sites across 1 country: United States