NCT02738229

Should We Use Oral Valacyclovir in Acute Herpetic Gingivostomatitis in Children?

Should We Use Oral Valacyclovir in Acute Herpetic Gingivostomatitis in Children? A Randomized Controlled Trial

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 80 (actual)
• Sponsor: St. Justine's Hospital · Academic / Other
• Sex: All
• Age: 1 Year – 8 Years
• Healthy volunteers: Not accepted

Summary

Primary herpetic gingivostomatitis is a frequent problem in pediatrics. Complications of this are dehydration, pain and hospitalisation. The objective of this randomized controlled trial is to assess the clinical efficacy of oral Valacyclovir to decrease the duration of symptoms associated with acute herpes gingivostomatitis in children. This study will involve 80 children aged 1 to 8 years old to receive weight adjusted doses of valacyclovir for 7 days. The primary outcome measure will be the duration (in days) of feeding and/or drinking difficulties.

Conditions

• Herpetic Gingivostomatitis

Interventions

Type	Name	Description
DRUG	Valacyclovir
DRUG	placebo

Timeline

• Start date: 2016-07-01
• Primary completion: 2022-12-01
• Completion: 2022-12-01
• First posted: 2016-04-14
• Last updated: 2023-04-11

Locations

1 site across 1 country: Canada