NCT02734251

Effect of Relora Supplement on Anxiety, Cognitive Performance & Mood Tested After Induced Stress

Effects of Magnolia and Phellodendron (Magnolia Officinalis and Phellodendron Amurense) Bark Extracts on Anxiety, Cognitive Performance, and Mood Tested After Induced Stress

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 36 (actual)
• Sponsor: InterHealth Nutraceuticals, Inc. · Industry
• Sex: All
• Age: 21 Years – 59 Years
• Healthy volunteers: Accepted

Summary

The present randomized, double-blind, placebo-controlled crossover trial aims to evaluate the effects of Relora supplementation on responses to induced stress produced by a combination of cognitive and physiologic stressors in healthy men and women. The effects of the supplement, compared with a placebo, will be evaluated using measures to assess anxiety \[State-Trait Anxiety Inventory-Part 1 (STAI-Part 1), mood \[Bond-Lader Visual Analog Scale (VAS)\], hypothalamic-pituitary-adrenal axis activation (salivary cortisol) and cognitive function (cognitive flexibility, reaction time, processing speed, attention, sustained attention, working memory, and executive function). Testing will be completed at the beginning and end of 7-d supplementation periods with the active and placebo products to assess both the acute effects and the "acute-on-chronic" effects following one week of daily use.

Conditions

• Mood (Psychological Function)

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Relora	750 mg/day
DIETARY_SUPPLEMENT	Placebo

Timeline

• Start date: 2016-02-01
• Primary completion: 2016-05-01
• First posted: 2016-04-12
• Last updated: 2016-05-24

Locations

1 site across 1 country: United States