NCT02731235

The Effect of Aerobic Exercise in Patients With Lacunar Stroke

High-intensity Training in Patients With Lacunar Stroke (HITPALS)

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 71 (estimated)
• Sponsor: Herlev Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

In a randomized-controlled study the effect of high-intensity training, 5 days a week at home for 12 weeks is tested in patients with lacunar stroke.

Detailed description

Little is known about effect of exercise for patients with lacunar stroke, no studies have investigated the feasibility or effect of aerobic exercise in this subgroup of stroke. The patients have few and temporary symptoms and are therefore early discharged from the hospital. After an cerebral infarct the patients have increased risk of recurrent stroke and they are at risk of developing cognitive deficits or vascular dementia over time. Researchers want to investigate if high-intensity training at home in the acute phase has an effect on aerobic fitness, endothelial response and health profile in this potential fragile group of patients. We hope to increase the patients´ physical and mental function, and thereby prevent a recurrent stroke and slow the progression of vascular diseases.

Conditions

• Stroke, Lacunar

Interventions

Type	Name	Description
OTHER	High-intensity training	high intensity training 5 days a week for 12 weeks
DRUG	prophylactic stroke medication	Usual care medication for stroke prophylaxis
BEHAVIORAL	Recommendations for lifestyle changes	Advise on diet, alcohol, smoking and exercise

Timeline

• Start date: 2016-01-01
• Primary completion: 2023-04-01
• Completion: 2024-03-01
• First posted: 2016-04-07
• Last updated: 2022-09-07

Locations

1 site across 1 country: Denmark