Trials / Completed
CompletedNCT02731183
Efficacy and Safety of Fecal Microbiota Transplantation for Chronic Intestinal Pseudo-obstruction
Efficacy and Safety of Fecal Microbiota Transplantation in Treatment of Chronic Intestinal Pseudo-obstruction: a Preliminary Study
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 9 (actual)
- Sponsor
- Jinling Hospital, China · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
Chronic intestinal pseudo obstruction(CIPO) is a serious motility disorder with life-threatening condition, and it is often related with bacterial overgrowth. Fecal microbiota transplantation (FMT) results in restoration of the normal intestinal microbial community structure. The investigators planned to observe the efficacy of FMT in the treatment of a series CIPO patients. Patients received FMT on 6 consecutive days through nasojejunal tubes and followed up for 8 weeks after treatment. Rate of clinical improvement and remission, feeding tolerance of enteral nutrition, CT score of intestinal obstruction, and gastrointestinal quality-of-life index(GIQLI) were evaluated.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | fecal microbiota transplantation | Patients received frozen FMT on 6 consecutive days through nasojejunal tubes. |
Timeline
- Start date
- 2014-12-01
- Primary completion
- 2015-09-01
- Completion
- 2016-03-01
- First posted
- 2016-04-07
- Last updated
- 2017-08-09
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT02731183. Inclusion in this directory is not an endorsement.