NCT02730533

The Efficacy of Esomeprazole Premedication on Intraoperative Bleeding During Gastric ESD

The Efficacy of Esomeprazole Premedication on Intraoperative Bleeding During Gastric ESD: an Endoscopist-blinded Randomized Controlled Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 74 (actual)
• Sponsor: Xijing Hospital of Digestive Diseases · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This will be a single-centre, randomised, endoscopist-blind, parallel-group study in patients who are scheduled endoscopic submucosal dissection (ESD) for gastric mucosal lesion. The primary objective is to observe whether a regimen of 7-day oral esomeprazole premedication can alleviate intraoperative bleeding in patients scheduled for ESD due to gastric mucosal lesions.

Conditions

• Stomach Neoplasms

Interventions

Type	Name	Description
DRUG	Esomeprazole	Proton pump inhibitor
DRUG	No PPI treatment	No PPI treatment before ESD procedure

Timeline

• Start date: 2016-03-01
• Primary completion: 2017-03-01
• Completion: 2017-04-01
• First posted: 2016-04-06
• Last updated: 2017-07-21

Locations

1 site across 1 country: China