NCT02726672

Fatigue and Inspiratory Muscles Training in Patients With Multiple Sclerosis

Fatigue and Inspiratory Muscles Training Against Resistance in Patients With Multiple Sclerosis With Severe Disabilities

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: 46 (actual)
• Sponsor: Lille Catholic University · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to assess the effect of a training of the inspiratory muscles against resistance at home during 10 weeks in multiple sclerosis patients with a severe disability.

Detailed description

Patients will be informed about the study procedures during a follow-up consultation or an hospitalization in a Physical and Rehabilitation Medicine Unit. If they give their informed consent to participate in the study, an investigator will randomize them into one of the 2 arms of the study. This study consists of 3 visits. The first visit (inclusion) is planned at day 0, the second visit 10 weeks later and the third 3 months after day 0. A patient who is randomized in the experimental arm will have to follow 10 weeks of rehabilitation of the inspiratory muscles at home between first and second visit. During this period, investigators will call these patients once a week to assess the compliance with the rehabilitation. The patients who have been randomized in the control group will not follow this rehabilitation program.

Conditions

• Multiple Sclerosis

Interventions

Type	Name	Description
DEVICE	respiratory rehabilitation using Powerbreathe	10 minutes 2 times a day : 30 inspirations per session during 10 weeks

Timeline

• Start date: 2016-02-01
• Primary completion: 2018-05-01
• Completion: 2018-11-01
• First posted: 2016-04-04
• Last updated: 2018-11-23

Locations

1 site across 1 country: France