NCT02723903

Hierarchical Treatment Based on Somatization Symptom Checklist

Efficacy of Hierarchical Treatment For Suspected Coronary Heart Disease Based on Somatization Symptom Checklist and Coronary Angiography

• Status: Unknown
• Phase: Phase 1 / Phase 2
• Study type: Interventional
• Enrollment: 200 (estimated)
• Sponsor: RenJi Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

A comparative study is conducted on the patients with suspected coronary artery disease (CAD). The patient will undergo coronary angiography after a somatic symptom scale (SSS) survey is carried out combining with Patient Health Questionnaire (PHQ-9) and Generalized Anxiety Disorder 7-items (GAD-7). Patient is then treated according to the checklist score and coronary angiography result. The efficacy, sensitivity and specificity of the SSS checklist will be evaluated during following up.

Detailed description

The presentation of physical complaints such as chest discomfort suggestive of suspicious coronary artery disease (CAD) but remain unexplained after negative finding from coronary angiography represents one of the most frustrating and puzzling problems in clinical medicine.A comparative study is conducted on the patients with suspected coronary artery disease. A somatic symptom scale (SSS) survey is carried out combining with Patient Health Questionnaire (PHQ-9) and Generalized Anxiety Disorder 7-items (GAD-7). Patient is treated according to the checklist score and coronary angiography result. Three surveys will be re-conducted 2 weeks after treatment. The sensitivity and specificity of the SSS checklist will be evaluated during following up.

Conditions

• Syndrome X

Interventions

Type	Name	Description
DRUG	Deanxit	we use Deanxit for the patient with anxiety
DRUG	Prozac	we use Prozac for the patient with depression
PROCEDURE	coronary artery disease treatment	including medication, coronary artery stent implantation according to the severity of stenosis of the coronary arteries

Timeline

• Start date: 2015-12-01
• Primary completion: 2020-12-01
• Completion: 2021-12-01
• First posted: 2016-03-31
• Last updated: 2020-03-04

Locations

1 site across 1 country: China