NCT02719119

Trial of Monthly Versus Bi-weekly Endoscopic Variceal Ligation for the Prevention of Esophageal Variceal Rebleeding

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: West China Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

Many physicians suggest repeating EVL every 1-2 weeks until esophageal varices are obliterated to prevent variceal rebleeding， however, the evidences supporting the efficacy of EVL intervals of 1-2 weeks are insufficient.This randomized controlled study was conducted in order to compare the long-term results of EVL when performed at two different results from monthly and bi-weekly treatments.

Detailed description

Endoscopic variceal ligation (EVL) is a safe and simple procedure now being used on a widening scale. A lot of patients who undergo endoscopic treatment for esophageal varices eventually require additional treatment for recurrent varices. Many physicians suggest repeating EVL every 1-2 weeks until esophageal varices are obliterated to prevent variceal rebleeding， however, the evidences supporting the efficacy of EVL intervals of 1-2 weeks are insufficient.This randomized controlled study was conducted in order to compare the long-term results of EVL when performed at two different results from monthly and bi-weekly treatments.

Conditions

• Esophageal and Gastric Varices

Interventions

Type	Name	Description
PROCEDURE	monthly Endoscopic Variceal Ligation (EVL)	Patients in this group will underwent endoscopic variceal ligation monthly.
PROCEDURE	bi-weekly Endoscopic Variceal Ligation (EVL)	Patients in this group will underwent endoscopic variceal ligation bi-weekly.

Timeline

• Start date: 2016-03-01
• Primary completion: 2017-06-01
• Completion: 2018-02-01
• First posted: 2016-03-25
• Last updated: 2017-04-05

Locations

1 site across 1 country: China