NCT02718859

Combination of Irreversible Electroporation and NK Immunotherapy for Advanced Pancreatic Cancer

Study of the Combined Therapy of Irreversible Electroporation（IRE） and Nature Killer (NK) Cells for Advanced Pancreatic Cancer

• Status: Completed
• Phase: Phase 1 / Phase 2
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: Fuda Cancer Hospital, Guangzhou · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to evaluate the safety and efficacy of the combined therapy using irreversible electroporation（IRE）and nature killer(NK) cells for advanced pancreatic cancer.

Detailed description

By enrolling patients with pancreatic cancer adapted to enrolled criteria, this study will document for the first time the safety and the short and long term efficacy of the combined therapy using irreversible electroporation（IRE）and nature killer（NK） cells for advanced pancreatic cancer. The efficacy will be evaluated according to relief degree,progress free survival(PFS) and overall survival(OS). The safety will be evaluated by statistics of adverse reaction

Conditions

• Pancreatic Cancer

Interventions

Type	Name	Description
BIOLOGICAL	NK cells	The pancreatic cancer patients will receive nature killer(NK) cells infusions,qd
PROCEDURE	irreversible electroporation (IRE )	The pancreatic cancer patients will receive the therapy of irreversible electroporation (IRE )

Timeline

• Start date: 2016-03-01
• Primary completion: 2017-03-01
• Completion: 2019-03-01
• First posted: 2016-03-24
• Last updated: 2019-09-12

Locations

1 site across 1 country: China