Trials / Completed
CompletedNCT02716753
Effects of Seminal Plasma on Pregnancy Rate With IVF
The Effects of Male Factors on the Success Rate of in Vitro Fertilization. Will Deposition of Seminal Plasma Around the External Cervical os Increase Pregnancy Rate?
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 1,600 (actual)
- Sponsor
- Ostergotland County Council, Sweden · Academic / Other
- Sex
- Female
- Age
- 20 Years – 40 Years
- Healthy volunteers
- Not accepted
Summary
All couples planned for IVF will be asked to participate. After information and received informed consent they will be randomized into two groups. At the time for ovum pick up during an IVF procedure either half of the amount of seminal plasma or the same amount of physiological NaCl solution will be installed around the external cervical opening in vagina. The syringe with seminal plasma or physiological NaCl solution will be prepared according to a prearranged randomization list by a technician. The success rate will be the number of diagnosed pregnancies and live births.
Detailed description
All couples planned for IVF will be asked to participate. After information and received informed consent they will be randomized into two groups. At the time for ovum pick up during an IVF procedure either half of the amount of seminal plasma or the same amount of physiological NaCl solution will be installed around the external cervical opening in vagina. Normally we do not use the seminal plasma but now half of it will be installed and the other half analysed regarding a number of cytokines possibly involved in the immunological preparation of the female internal genitalia. The syringe with seminal plasma or physiological NaCl solution will be prepared according to a prearranged randomization list by a technician.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| BIOLOGICAL | seminal plasma | |
| BIOLOGICAL | Physiological NaCL solution |
Timeline
- Start date
- 2016-11-01
- Primary completion
- 2023-03-01
- Completion
- 2023-03-01
- First posted
- 2016-03-23
- Last updated
- 2023-10-02
Locations
1 site across 1 country: Sweden
Source: ClinicalTrials.gov record NCT02716753. Inclusion in this directory is not an endorsement.