Clinical Trials Directory

Trials / Completed

CompletedNCT02716402

Cyanotic Heart Disease and Thrombosis

Cyanotic Congenital Heart Disease: Prevalence of Pulmonary and Cerebral Thrombi-embolic Events

Status
Completed
Phase
N/A
Study type
Interventional
Enrollment
50 (actual)
Sponsor
Annette Schophuus Jensen · Academic / Other
Sex
All
Age
18 Years – 100 Years
Healthy volunteers
Not accepted

Summary

The purpose of the study is to examine previously examined patients with cyanotic congenital heart disease to assess how many of the patients have obtained additional blood clots since they were examined 8 years ago.

Detailed description

Patients with cyanotic congenital heart disease have reduced oxygen content in their blood due to abnormal connection between the heart's right and left sides. The reduced oxygenation of the blood affects several organs of the body and a common complications to the disease is blood clots. Despite the patients are young and do not have typical risk factors, previous studies have shown, that they have a very high prevalence of thrombosis in the lungs and brain. The reason for the increased prevalence of blood clots is not known. A previous study investigated the prevalence of blood clots systematically in patients with cyanotic congenital heart disease and found that approximately 30-40% of the patients had had a clot in the lung or brain. Thus, the study could not predict, when the patient had had a thrombotic event, and most of the patients did not previously had imaging performed. Therefore the aim of this study is to re-examine previously examined cyanotic patients regardless of previous medical history, to assess how many of the patients have obtained additional blood clots since they were examined 8 years ago.

Conditions

Interventions

TypeNameDescription
RADIATIONCerebral MRI and V/Q SPECT/CTCerebral MRI and V/Q SPECT/CT

Timeline

Start date
2015-11-01
Primary completion
2017-05-01
Completion
2017-11-01
First posted
2016-03-23
Last updated
2018-08-29

Locations

1 site across 1 country: Denmark

Source: ClinicalTrials.gov record NCT02716402. Inclusion in this directory is not an endorsement.