Trials / Completed
CompletedNCT02714205
Flushing Reduction Associated With Nitrates
- Status
- Completed
- Phase
- Phase 2
- Study type
- Interventional
- Enrollment
- 141 (actual)
- Sponsor
- Alison Huang, MD · Academic / Other
- Sex
- Female
- Age
- 40 Years – 62 Years
- Healthy volunteers
- Accepted
Summary
A randomized, double-blinded, placebo-controlled trial of uninterrupted transdermal nitrate therapy in 140 peri- or postmenopausal women who have frequent hot flashes. Women will be randomly assigned to uninterrupted use of transdermal nitrate therapy (participant directed dose-escalation of 0.2 to 0.6 mg/hr) or identical-appearing placebo patches for 12 weeks.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | transdermal nitroglycerin | Study participants will be randomized to transdermal nitroglycerin patch or placebo patch. Participants will wear a study medication patch daily, for 12 weeks. |
| DRUG | Placebo | Study participants will be randomized to transdermal nitroglycerin patch or placebo patch. Participants will wear a study medication patch daily, for 12 weeks. |
Timeline
- Start date
- 2017-04-24
- Primary completion
- 2022-03-08
- Completion
- 2022-04-05
- First posted
- 2016-03-21
- Last updated
- 2025-03-28
- Results posted
- 2023-05-18
Locations
2 sites across 1 country: United States
Regulatory
- FDA-regulated drug study
Source: ClinicalTrials.gov record NCT02714205. Inclusion in this directory is not an endorsement.