NCT02712190

Evaluation of Prolonged Apnea Supported by High Frequency Non-invasive Ventilation.

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (estimated)
• Sponsor: Centre Hospitalier Universitaire Vaudois · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The purpose of the study is to assess the efficacy of high-frequency non-invasive ventilation on apnea duration, carbon dioxide clearance and oxygen delivery in healthy subjets and patients with lung disease.

Detailed description

High frequency ventilation (HF-V) allows to ensure oxygen delivery and carbon dioxide clearance despite the absence of thoracic movement in anesthetized, invasively ventilated subjects. This same technique could be applied by a non-invasive interface (HF-NIV), allowing to obtain a prolonged apnea (absence of thoraco-abdominal respiratory movements) in awaken subjects. Such an application would be of interest for several clinical applications, e.g. lung imaging and radio-therapy treatment on lung cancer. The purpose of the study is to assess the effect of different HF-NIV setting on the apnea duration, carbon dioxide clearance and oxygen delivery in healthy subjets and patients with lung diseases.

Conditions

• Non-invasive Ventilation
• High-frequency Ventilation
• Healthy Volunteer
• Lung Diseases

Interventions

Type	Name	Description
DEVICE	High-frequency non-invasive ventilation	Comparison of 2 different settings of HF-NIV

Timeline

• Start date: 2016-03-01
• Primary completion: 2022-09-01
• Completion: 2022-09-01
• First posted: 2016-03-18
• Last updated: 2020-08-05

Locations

1 site across 1 country: Switzerland