NCT02710552

Low-dose Combination of Three Antihypertensive Drugs

Randomized Comparison of Fixed Low-dose Combination of THREE Antihypertensive Drugs Versus Fixed High-dose Combination of Two Antihypertensive Drugs in Arterial Hypertension (the 3D Trial)

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 100 (estimated)
• Sponsor: University of Roma La Sapienza · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

The aim of the study is to compare the efficacy and safety of low-dose combination of three antihypertensive drugs versus fixed high-dose combination of two antihypertensive drugs in arterial hypertension

Detailed description

The aim of the study is to compare the efficacy and safety of commercially available low-dose combination of three antihypertensive drugs versus commercially available fixed high-dose combination of two antihypertensive drugs in arterial hypertension

Conditions

• Arterial Hypertension

Interventions

Type	Name	Description
DRUG	Tripliam (perindopril, indapamide, amlodipine)	Fixed combination of perindopril 5 mg, indapamide 1,25 and amlodipine 5 mg
DRUG	Reaptan (perindopril, amlodipine)	Fixed combination of perindopril 10 mg and amlodipine 5 mg

Timeline

• Start date: 2016-04-01
• Primary completion: 2019-03-01
• Completion: 2020-03-01
• First posted: 2016-03-16
• Last updated: 2016-03-17

Locations

1 site across 1 country: Italy