NCT02708628

The Efficacy of Extract of Allium Cepae, Allantoin and Heparin in Patients With Proven Scar Development

The Efficacy of Prophylactic Use of Extract of Allium Cepae, Allantoin and Heparin in Patients With Proven Scar Development After Excision of Previous Scar

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 120 (actual)
• Sponsor: Suleymaniye Birth And Women's Health Education And Research Hospital · Other Government
• Sex: Female
• Age: 18 Years – 40 Years
• Healthy volunteers: Accepted

Summary

To investigate the efficacy of prophylactic use of a topical gel containing extract of allium cepae, allantoin and heparin after surgical removal of the primary cesarean scar in the second cesarean section.

Detailed description

120 patients who are admitted for the second cesarean delivery, not taking prophylactic medication after the first cesarean section, whose scar development and measurements are taken will be included in the study. First caesarean section scars will be removed surgically for all patients. 60 out of 120 patients (treatment group) will use prophylactic topical scar gel 2 times in a day, and remaining 60 patients (control group )won't use. The efficacy of the drug will be evaluated by taking strict measurements of the incision and POSAS (The Patient and Observer Scar Assessment Scale) and Vancouver Scales at 6.12 and 24 weeks. Steps; 1. Observation of the primary cesarean scar by taking scar measurements and using Vancouver and POSAS scales. 2. Surgical removal of the primary cesarean scar in the second cesarean section. 3. 24 weeks topical application of gel containing extract of allium cepae, allantoin and heparin(only treatment group). 4. Observation of the skin incision at 6,12 and 24 weeks by taking scar measurements with using Vancouver and POSAS scales.

Conditions

• Cicatrix

Interventions

Type	Name	Description
DRUG	extract of allium cepae, allantoin and heparin	prophylactic use of a topical gel containing extract of allium cepae, allantoin and heparin two times in a day after second c-section
PROCEDURE	Scar excision	Scar excision in second c-section

Timeline

• Start date: 2015-12-01
• Primary completion: 2016-04-01
• Completion: 2016-10-01
• First posted: 2016-03-15
• Last updated: 2016-10-04

Locations

1 site across 1 country: Turkey (Türkiye)