NCT02706587

Neuromuscular Electrical Stimulation for Intensive Care Unit-acquired Weakness Assessment

Neuromuscular Electrical Stimulation for Intensive Care Unit-acquired Weakness

• Status: Unknown
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 102 (estimated)
• Sponsor: Institut Mutualiste Montsouris · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to determine whether early neuromuscular electrical stimulation is effective in the prevention of neuromuscular weakness in critical ill patients.

Detailed description

Randomized, controlled study of early electrical neurostimulation (vs sham) in critically ill patients.

Conditions

• Polyneuropathy, Critical Illness

Interventions

Type	Name	Description
DEVICE	Neuromuscular electrical stimulation	NEMS is delivered bilaterally to the quadriceps femoris muscle using a portable battery-powered stimulator (Rehab 400, Cefar Compex, France). The electrodes are placed on the motor points of vastus medialis and vastus lateralis muscles. Electrical stimuli of 45Hz (pulse width: 380 µseconds; 6 seconds on with 1.5 second rise time; and 0.75 seconds fall time.; 5 seconds off). The current is adjusted to ensure maximum tolerable muscle contraction The protocol is applied twice daily for 25 minutes, five days a week.
DEVICE	Sham control	No electrostimulation

Timeline

• Start date: 2016-03-01
• Primary completion: 2018-04-01
• Completion: 2018-06-01
• First posted: 2016-03-11
• Last updated: 2016-09-13

Locations

1 site across 1 country: France