NCT02704507

Addition of a Topical Steroid to a Topical Retinoid in Acne Patients

Addition of a Topical Steroid to a Topical Retinoid: a Randomized, Split-face, Placebo-controlled, Double-blind, Single-center Clinical Study

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 20 (actual)
• Sponsor: Carilion Clinic · Academic / Other
• Sex: All
• Age: 12 Years
• Healthy volunteers: Accepted

Summary

A randomized, split-face, placebo-controlled, double-blind, single-center clinical trial comparing topical retinoid on half the face and retinoid plus topical steroid on the other half.

Detailed description

A randomized, split-face, placebo-controlled, double-blind, single-center clinical trial wherein 20 patients received daily 0.05% tretinoin with one half of the face receiving triamcinolone 0.025% and the other half an inert emollient for 4 weeks. Subjects continued applying tretinoin 0.05% daily to the bilateral face without triamcinolone or emollient for an additional 4 weeks. Investigator's Global Assessment, lesion counts, and study subject's self-assessments of burning/stinging, itching, erythema, and dryness/scaling will be collected at 1, 2, 4, and 8 weeks.

Conditions

• Acne

Interventions

Type	Name	Description
DRUG	Triamcinolone	topical application nightly to half the face for 4 weeks
DRUG	Tretinoin	topical application nightly for 8 weeks
DRUG	Emollient	topical application nightly to half the face for 4 weeks

Timeline

• Start date: 2015-06-01
• Primary completion: 2016-01-01
• Completion: 2016-06-01
• First posted: 2016-03-10
• Last updated: 2016-03-10