NCT02702973

Characteristic Analysis of Retinopathy Associated With High Doses of Interferon α-2b Therapy

Characteristic Analysis of Retinopathy Associated With High Doses of Interferon α-2b Therapy in Patients With Melanomas of the Skin

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 1 (estimated)
• Sponsor: The First Hospital of Jilin University · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

The high doses of interferon α-2b therapy in patients with melanomas of the skin may induced retinopathy, especially in the patients with hypertension or diabetes, so these patients should be followed up after treatment.

Detailed description

Patients with melanomas of the skin whose tumors have been resected completely were collected. The detailed ocular examinations including intraocular pressure, slit lamp microscope, indirect ophthalmoscope and color fundus photography were done before the induction therapy, 2 weeks after the induction therapy, after the whole course of induction therapy and each month in the maintenance treatment period. Fundus examinations were carried out by experienced ocular fundus doctors and the retinopathy characteristics were recorded.

Conditions

• Retinopathy

Interventions

Type	Name	Description
OTHER	Observe the fundus characteristics after therapy.

Timeline

• Start date: 2015-12-01
• Primary completion: 2017-10-01
• Completion: 2017-10-01
• First posted: 2016-03-09
• Last updated: 2016-03-09

Locations

1 site across 1 country: China