NCT02697942

Hemodialysis-based Interventions to Preserve Cognitive Function

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: 24 (actual)
• Sponsor: Johns Hopkins Bloomberg School of Public Health · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This will be a pilot, single center, randomized, controlled trial to slow cognitive decline in adults undergoing hemodialysis (HD). The investigators will test two interventions (cognitive training and exercise training) against the standard of care.

Detailed description

This will be a pilot, single center, randomized, controlled trial to slow cognitive decline in adults undergoing hemodialysis (HD). The investigators primary objective is to demonstrate feasibility for the interventions (cognitive training and exercise training) in Aim 1. The investigators will formally test whether whether cognitive training (tablet-based brain games) and exercise training (stationary foot pedal) administered during HD slow cognitive decline as well as improve secondary outcomes (physical function, frailty, and health-related quality of life (HRQOL) as part of Aim 2. The investigators will compare these two interventions against the standard of care. Pre- and post-intervention assessments will be conducted at the dialysis unit by a study coordinator and by research assistants. Participants will be followed for 6 months to assess cognitive decline.

Conditions

• Kidney Failure, Chronic

Interventions

Type	Name	Description
OTHER	cognitive training	The investigators will provide participants with tablets to play brain games through Lumosity.
OTHER	exercise training	The investigators will provide participants with foot peddlers.

Timeline

• Start date: 2016-02-01
• Primary completion: 2017-07-01
• Completion: 2017-11-20
• First posted: 2016-03-03
• Last updated: 2018-04-19

Locations

1 site across 1 country: United States