Trials / Completed
CompletedNCT02695771
The Bladder Instillation Comparison Study
A Prospective, Open-label Randomized Clinical Trial of a Single Bladder Instillation of Mitomycin C vs. Gemcitabine vs. No Additional Treatment Immediately After Transurethral Resection of Bladder Tumor (TURBT)
- Status
- Completed
- Phase
- Phase 3
- Study type
- Interventional
- Enrollment
- 101 (actual)
- Sponsor
- Corewell Health West · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
To compare the efficacy of Mitomycin C vs. Gemcitabine vs. no adjuvant treatment as a single intraoperative instillation in preventing recurrence of bladder cancer.
Detailed description
This study will compare standard of care treatment for patients with non-muscle invasive bladder cancer (NMIBC). Patients will be randomized to one of three arms, Mitomycin C, Gemcitabine or no additional treatment immediately following TURBT in the operating suite. All treatment, surgical procedures and follow up care will be conducted according to standard of care treatment.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Mitomycin C | Cancer chemotherapeutic agent |
| DRUG | Gemcitabine | Cancer chemotherapeutic agent |
Timeline
- Start date
- 2016-04-19
- Primary completion
- 2021-10-22
- Completion
- 2021-10-22
- First posted
- 2016-03-01
- Last updated
- 2023-04-21
- Results posted
- 2023-04-21
Locations
3 sites across 1 country: United States
Source: ClinicalTrials.gov record NCT02695771. Inclusion in this directory is not an endorsement.