Trials / Unknown
UnknownNCT02693912
Changes in Alveolar Macrophage Function During Acute Lung Injury
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 25 (estimated)
- Sponsor
- West China Hospital · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Accepted
Summary
In this study, the investigators aim to observe the change in alveolar macrophage function during acute lung injury.
Detailed description
Alveolar macrophages are tissue-resident or recruited cells with key functions in recognition of pathogens, initiation of host defensive ang protective inflammation,and in clearance of pathogens from the airways. However, macrophages are also responsible for efficient clearance of apoptotic neutrophils, termed efferocytosis, which is a prerequisite for the timely resolution of inflammation. In this study, the investigators aim to observe the change in alveolar macrophage function during acute lung injury.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Bronchoscopy | Bronchoscopy will be implemented under sedation in both groups. |
Timeline
- Start date
- 2016-09-01
- Primary completion
- 2017-12-01
- Completion
- 2018-08-01
- First posted
- 2016-02-29
- Last updated
- 2016-02-29
Source: ClinicalTrials.gov record NCT02693912. Inclusion in this directory is not an endorsement.